Garcia-Garrote, M., Perez-Villalba, A., Garrido-Gil, P., Belenguer, G., Parga, J. A., Perez-Sanchez, F., Labandeira-Garcia, J. L., Farinas, I. and Rodriguez-Pallares, J. (2019). «Interaction between Angiotensin Type 1, Type 2, and Mas Receptors to Regulate Adult Neurogenesis in the Brain Ventricular-Subventricular Zone.» Cells 8(12).

The renin-angiotensin system (RAS), and particularly its angiotensin type-2 receptors [...]

Por |2026-06-02T17:44:37+01:0019 de noviembre de 2020||11 Comentarios

Perez-Villalba, A., Sirerol-Piquer, M. S., Belenguer, G., Soriano-Canton, R., Munoz-Manchado, A. B., Villadiego, J., Alarcon-Aris, D., Soria, F. N., Dehay, B., Bezard, E., Vila, M., Bortolozzi, A., Toledo-Aral, J. J., Perez-Sanchez, F. and Farinas, I. (2018). «Synaptic Regulator alpha-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells.» J Neurosci 38(4): 814-825.

Synaptic protein alpha-synuclein (alpha-SYN) modulates neurotransmission in a complex and [...]

Por |2026-06-02T17:44:37+01:0018 de noviembre de 2020||Comentarios desactivados en Perez-Villalba, A., Sirerol-Piquer, M. S., Belenguer, G., Soriano-Canton, R., Munoz-Manchado, A. B., Villadiego, J., Alarcon-Aris, D., Soria, F. N., Dehay, B., Bezard, E., Vila, M., Bortolozzi, A., Toledo-Aral, J. J., Perez-Sanchez, F. and Farinas, I. (2018). «Synaptic Regulator alpha-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells.» J Neurosci 38(4): 814-825.

Soriano-Canton, R., Perez-Villalba, A., Morante-Redolat, J. M., Marques-Torrejon, M. A., Pallas, M., Perez-Sanchez, F. and Farinas, I. (2015). «Regulation of the p19(Arf)/p53 pathway by histone acetylation underlies neural stem cell behavior in senescence-prone SAMP8 mice.» Aging Cell 14(3): 453-462.

Brain aging is associated with increased neurodegeneration and reduced neurogenesis. [...]

Por |2026-06-02T17:44:37+01:0015 de noviembre de 2020||5 Comentarios

Delgado, A. C., Ferron, S. R., Vicente, D., Porlan, E., Perez-Villalba, A., Trujillo, C. M., D’Ocon, P. and Farinas, I. (2014). «Endothelial NT-3 delivered by vasculature and CSF promotes quiescence of subependymal neural stem cells through nitric oxide induction.» Neuron 83(3): 572-585.

Interactions of adult neural stem cells (NSCs) with supportive vasculature [...]

Por |2026-06-02T17:44:37+01:0014 de noviembre de 2020||Comentarios desactivados en Delgado, A. C., Ferron, S. R., Vicente, D., Porlan, E., Perez-Villalba, A., Trujillo, C. M., D’Ocon, P. and Farinas, I. (2014). «Endothelial NT-3 delivered by vasculature and CSF promotes quiescence of subependymal neural stem cells through nitric oxide induction.» Neuron 83(3): 572-585.

Porlan, E., Marti-Prado, B., Morante-Redolat, J. M., Consiglio, A., Delgado, A. C., Kypta, R., Lopez-Otin, C., Kirstein, M. and Farinas, I. (2014). «MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.» Nat Cell Biol 16(7): 629-638.

The identification of mechanisms that maintain stem cell niche architecture [...]

Por |2026-06-02T17:44:37+01:0014 de noviembre de 2020||Comentarios desactivados en Porlan, E., Marti-Prado, B., Morante-Redolat, J. M., Consiglio, A., Delgado, A. C., Kypta, R., Lopez-Otin, C., Kirstein, M. and Farinas, I. (2014). «MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.» Nat Cell Biol 16(7): 629-638.

Recasens, A., Dehay, B., Bove, J., Carballo-Carbajal, I., Dovero, S., Perez-Villalba, A., Fernagut, P. O., Blesa, J., Parent, A., Perier, C., Farinas, I., Obeso, J. A., Bezard, E. and Vila, M. (2014). «Lewy body extracts from Parkinson disease brains trigger alpha-synuclein pathology and neurodegeneration in mice and monkeys.» Ann Neurol 75(3): 351-362.

OBJECTIVE: Mounting evidence suggests that alpha-synuclein, a major protein component [...]

Por |2026-06-02T17:44:37+01:0014 de noviembre de 2020||3.084 Comentarios
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