Garcia-Garrote, M., Perez-Villalba, A., Garrido-Gil, P., Belenguer, G., Parga, J. A., Perez-Sanchez, F., Labandeira-Garcia, J. L., Farinas, I. and Rodriguez-Pallares, J. (2019). «Interaction between Angiotensin Type 1, Type 2, and Mas Receptors to Regulate Adult Neurogenesis in the Brain Ventricular-Subventricular Zone.» Cells 8(12).

The renin-angiotensin system (RAS), and particularly its angiotensin type-2 receptors [...]

Por |2020-11-24T14:19:44+02:0019 de noviembre de 2020||Sin comentarios
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Perez-Villalba, A., Sirerol-Piquer, M. S., Belenguer, G., Soriano-Canton, R., Munoz-Manchado, A. B., Villadiego, J., Alarcon-Aris, D., Soria, F. N., Dehay, B., Bezard, E., Vila, M., Bortolozzi, A., Toledo-Aral, J. J., Perez-Sanchez, F. and Farinas, I. (2018). «Synaptic Regulator alpha-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells.» J Neurosci 38(4): 814-825.

Synaptic protein alpha-synuclein (alpha-SYN) modulates neurotransmission in a complex and [...]

Por |2020-11-24T14:19:50+02:0018 de noviembre de 2020||Sin comentarios
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Soriano-Canton, R., Perez-Villalba, A., Morante-Redolat, J. M., Marques-Torrejon, M. A., Pallas, M., Perez-Sanchez, F. and Farinas, I. (2015). «Regulation of the p19(Arf)/p53 pathway by histone acetylation underlies neural stem cell behavior in senescence-prone SAMP8 mice.» Aging Cell 14(3): 453-462.

Brain aging is associated with increased neurodegeneration and reduced neurogenesis. [...]

Por |2020-11-24T14:21:43+02:0015 de noviembre de 2020||Sin comentarios
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Recasens, A., Dehay, B., Bove, J., Carballo-Carbajal, I., Dovero, S., Perez-Villalba, A., Fernagut, P. O., Blesa, J., Parent, A., Perier, C., Farinas, I., Obeso, J. A., Bezard, E. and Vila, M. (2014). «Lewy body extracts from Parkinson disease brains trigger alpha-synuclein pathology and neurodegeneration in mice and monkeys.» Ann Neurol 75(3): 351-362.

OBJECTIVE: Mounting evidence suggests that alpha-synuclein, a major protein component [...]

Por |2020-11-24T14:21:34+02:0014 de noviembre de 2020||Sin comentarios
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