Marques-Torrejon, M. A., Porlan, E., Banito, A., Gomez-Ibarlucea, E., Lopez-Contreras, A. J., Fernandez-Capetillo, O., Vidal, A., Gil, J., Torres, J. and Farinas, I. (2013). «Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression.» Cell Stem Cell 12(1): 88-100.

In the adult brain, continual neurogenesis of olfactory neurons is [...]

Por |2020-11-24T14:19:18+02:0013 de noviembre de 2020||Sin comentarios

Porlan, E., Morante-Redolat, J. M., Marques-Torrejon, M. A., Andreu-Agullo, C., Carneiro, C., Gomez-Ibarlucea, E., Soto, A., Vidal, A., Ferron, S. R. and Farinas, I. (2013). «Transcriptional repression of Bmp2 by p21(Waf1/Cip1) links quiescence to neural stem cell maintenance.» Nat Neurosci 16(11): 1567-1575.

Relative quiescence and self renewal are defining features of adult [...]

Por |2020-11-24T14:19:25+02:0013 de noviembre de 2020||Sin comentarios

Ferron, S. R., Charalambous, M., Radford, E., McEwen, K., Wildner, H., Hind, E., Morante-Redolat, J. M., Laborda, J., Guillemot, F., Bauer, S. R., Farinas, I. and Ferguson-Smith, A. C. (2011). «Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis.» Nature 475(7356): 381-385.

The gene for the atypical NOTCH ligand delta-like homologue 1 [...]

Por |2020-11-24T14:19:04+02:0011 de noviembre de 2020||Sin comentarios

Ferron, S. R., Pozo, N., Laguna, A., Aranda, S., Porlan, E., Moreno, M., Fillat, C., de la Luna, S., Sanchez, P., Arbones, M. L. and Farinas, I. (2010). «Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling.» Cell Stem Cell 7(3): 367-379.

Stem cell division can result in two sibling cells exhibiting [...]

Por |2020-11-24T14:18:50+02:0010 de noviembre de 2020||Sin comentarios

Mira, H., Andreu, Z., Suh, H., Lie, D. C., Jessberger, S., Consiglio, A., San Emeterio, J., Hortiguela, R., Marques-Torrejon, M. A., Nakashima, K., Colak, D., Gotz, M., Farinas, I. and Gage, F. H. (2010). «Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.» Cell Stem Cell 7(1): 78-89.

Neural stem cells (NSCs) in the adult hippocampus divide infrequently, [...]

Por |2020-11-24T14:18:57+02:0010 de noviembre de 2020||2 Comentarios

Folgueras, A. R., Valdes-Sanchez, T., Llano, E., Menendez, L., Baamonde, A., Denlinger, B. L., Belmonte, C., Juarez, L., Lastra, A., Garcia-Suarez, O., Astudillo, A., Kirstein, M., Pendas, A. M., Farinas, I. and Lopez-Otin, C. (2009). «Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation.» Proc Natl Acad Sci U S A 106(38): 16451-16456.

Peripheral interactions between nociceptive fibers and mast cells contribute to [...]

Por |2020-11-24T14:18:35+02:009 de noviembre de 2020||Sin comentarios
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